Description

2-Bromo-4-(trifluoromethyl)nicotinic acid is a high-value, multi-functional heterocyclic building block. This compound is essential for the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors, due to its reactive bromine and trifluoromethyl substituents. It is primarily sought after by R&D chemists and process development scientists working on novel active ingredients, including kinase inhibitors and other biologically relevant scaffolds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for targeted therapies.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and insecticides where the trifluoromethyl group enhances bioavailability and stability.
• Material Science: Serves as a building block for advanced organic materials, such as ligands for catalysis or components for organic electronics.
• Chemical Biology: Employed in probe and tool compound discovery for studying biological pathways and target validation.
• Custom Synthesis: Utilized by contract research and manufacturing organizations (CROs/CMOs) for client-specific molecule construction.
• Academic Research: A valuable reagent for methodological development and exploring new chemical space in heterocyclic chemistry.

Basic Information

Product Name	2-Bromo-4-(trifluoromethyl)nicotinic Acid
CAS No.	749875-15-8
Molecular Formula	C7H3BrF3NO2
Molecular Weight	269.99 g/mol
Synonyms	2-Bromo-4-(trifluoromethyl)pyridine-3-carboxylic acid; 3-Pyridinecarboxylic acid, 2-bromo-4-(trifluoromethyl)-; 2-Bromo-4-trifluoromethylnicotinic acid; 749875-15-8; 2-Bromo-4-(trifluoromethyl)-3-pyridinecarboxylic acid
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-4-(trifluoromethyl)nicotinic acid is subjected to rigorous analytical testing to ensure identity, purity, and consistency. Our quality assurance protocols are designed to meet the stringent requirements of research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥95% by HPLC), identity confirmation, and impurity profile is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible materials. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥95%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.