Description

2-Bromo-6-(Trifluoromethyl)Isonicotinic Acid is a high-value, multi-functional heterocyclic building block used in advanced organic synthesis. Its core value lies in the strategic combination of a bromine substituent and a trifluoromethyl group on the pyridine ring, enabling precise molecular modifications. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used to construct novel herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a versatile scaffold for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the development of advanced organic electronic materials and liquid crystals.
• Custom Synthesis & Contract Manufacturing: A critical building block for custom synthesis houses serving the life sciences sector.
• Academic & R&D: Used in medicinal chemistry programs for structure-activity relationship (SAR) studies and library synthesis.

Basic Information

Product Name	2-Bromo-6-(Trifluoromethyl)Isonicotinic Acid
CAS No.	749875-11-4
Molecular Formula	C7H3BrF3NO2
Molecular Weight	269.99 g/mol
Synonyms	2-Bromo-6-(trifluoromethyl)pyridine-4-carboxylic acid; 4-Pyridinecarboxylic acid, 2-bromo-6-(trifluoromethyl)-; 6-(Trifluoromethyl)-2-bromoisonicotinic acid; 2-Bromo-6-trifluoromethylisonicotinic acid; 2-Bromo-6-trifluoromethyl-4-pyridinecarboxylic acid; 749875-11-4; BTFIA
EINECS	Contact for details

Quality Control

Our 2-Bromo-6-(Trifluoromethyl)Isonicotinic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and away from direct light sources to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.