Description

5-Chloro-6-Trifluoromethyl-Pyridine-2-Carboxylic Acid is a high-value, multi-functional pyridine derivative that serves as a critical building block in advanced chemical synthesis. Its unique trifluoromethyl and carboxylic acid functionalities make it an essential intermediate for creating compounds with enhanced biological activity and physicochemical properties. This product is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and production of active pharmaceutical ingredients (APIs), particularly in the development of receptor antagonists and enzyme inhibitors.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group improves lipophilicity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysts for organic transformations.
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic materials with specific electronic properties.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	5-Chloro-6-Trifluoromethyl-Pyridine-2-Carboxylic Acid
CAS No.	749875-06-7
Molecular Formula	C7H3ClF3NO2
Molecular Weight	225.55 g/mol
Synonyms	2-Pyridinecarboxylic acid, 5-chloro-6-(trifluoromethyl)-; 5-Chloro-6-(trifluoromethyl)picolinic acid; 5-Chloro-6-trifluoromethylpicolinic acid; 5-Chloro-6-trifluoromethyl-2-pyridinecarboxylic acid; 6-Trifluoromethyl-5-chloropicolinic acid; Picolinic acid, 5-chloro-6-(trifluoromethyl)-; 749875-06-7
EINECS	Contact for details

Quality Control

Our 5-Chloro-6-Trifluoromethyl-Pyridine-2-Carboxylic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.