Description

3-Chloro-2-(Trifluoromethyl)Isonicotinic Acid is a high-value, multi-functional heterocyclic building block characterized by its unique combination of chloro and trifluoromethyl substituents on the pyridine ring. This compound is essential for the synthesis of advanced pharmaceutical intermediates and agrochemicals, where its structure imparts critical biological activity and metabolic stability. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used to develop advanced herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Ligand and Catalyst Development: Serves as a building block for creating specialized ligands used in catalytic processes and material science.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new chemical entities and reaction pathways.
• Fluorinated Compound Production: Acts as a critical source of the trifluoromethyl group for introducing fluorine into target molecules to improve their properties.

Basic Information

Product Name	3-Chloro-2-(Trifluoromethyl)Isonicotinic Acid
CAS No.	749875-02-3
Molecular Formula	C7H3ClF3NO2
Molecular Weight	225.55 g/mol
Synonyms	3-Chloro-2-(trifluoromethyl)pyridine-4-carboxylic acid; 4-Pyridinecarboxylic acid, 3-chloro-2-(trifluoromethyl)-; 3-Chloro-2-trifluoromethylisonicotinic acid; 3-Chloro-2-(trifluoromethyl)-4-pyridinecarboxylic acid; 2-(Trifluoromethyl)-3-chloroisonicotinic acid; 749875-02-3; 3-Chloro-2-trifluoromethyl-4-pyridinecarboxylic acid
EINECS	Contact for details

Quality Control

Our production of 3-Chloro-2-(Trifluoromethyl)Isonicotinic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, NMR, and GC-MS to verify identity, potency, and impurity profiles. Certificates of Analysis (COA) documenting full specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is sensitive to strong bases and fluorides; keep away from incompatible materials. For long-term storage, consider using desiccants to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.