Description

(S)-3-Methyl-2-Butyl Isocyanate is a chiral, highly reactive organic intermediate of significant importance in asymmetric synthesis. Its value lies in its role as a key building block for introducing the (S)-3-methyl-2-butyl moiety into target molecules, enabling the creation of compounds with specific stereochemistry. This product is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity chiral intermediates for developing active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of active pharmaceutical ingredients (APIs) and investigational new drugs, particularly those targeting neurological and metabolic disorders.
• Agrochemical Synthesis: Used in the production of chiral pesticides, herbicides, and fungicides where specific stereochemistry is crucial for biological activity and environmental safety.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing chiral ligands and organocatalysts used in asymmetric catalysis.
• Polymer Modification: Employed to introduce chiral centers into polyurethanes and other specialty polymers, modifying their physical and mechanical properties.
• Peptide Mimetics & Conjugates: Useful for creating non-natural amino acid derivatives and isocyanate-based conjugates for biochemical research.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D in organic and medicinal chemistry for exploring new synthetic pathways.

Basic Information

Product Name	(S)-3-Methyl-2-Butyl Isocyanate
CAS No.	749261-38-9
Molecular Formula	C6H11NO
Molecular Weight	113.16 g/mol
Synonyms	(S)-3-Methylbutan-2-yl isocyanate; (S)-sec-Butyl isocyanate; (S)-1-Isocyanato-2-methylbutane; (2S)-3-Methyl-2-butyl isocyanate; (S)-2-Butyl isocyanate; L-3-Methyl-2-butyl isocyanate; (S)-(-)-3-Methyl-2-butyl isocyanate
EINECS	Contact for details

Quality Control

Our (S)-3-Methyl-2-Butyl Isocyanate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC and GC, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile and moisture-sensitive nature, store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated area. Recommended long-term storage temperature is 2-8°C. Keep away from strong bases, alcohols, amines, and other nucleophiles.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (Karl Fischer)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.