Description

Pyridine, 2-Chloro-4-Methyl-6-(Trifluoromethyl)- is a specialized halogenated and trifluoromethylated pyridine derivative, serving as a high-value synthetic intermediate in advanced chemical manufacturing. Its unique structure, combining chlorine and a trifluoromethyl group on the pyridine ring, makes it a critical building block for introducing specific steric and electronic properties into target molecules. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug candidates, particularly those requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the pyridine core and fluorine atoms contribute to efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized nitrogen-containing ligands used in transition metal catalysis and organic synthesis.
• Material Science Research: Employed in the synthesis of advanced organic materials, such as liquid crystals, organic semiconductors, and metal-organic frameworks (MOFs).
• Fluorine Chemistry: A valuable reagent for introducing the trifluoromethyl group into heterocyclic systems, a common strategy in modern medicinal and agrochemistry.

Basic Information

Product Name	Pyridine, 2-Chloro-4-Methyl-6-(Trifluoromethyl)-
CAS No.	749256-90-4
Molecular Formula	C7H5ClF3N
Molecular Weight	195.57 g/mol
Synonyms	2-Chloro-4-methyl-6-(trifluoromethyl)pyridine; 6-(Trifluoromethyl)-2-chloro-4-picoline; 2-Chloro-4-methyl-6-trifluoromethylpyridine; 2-Chloro-4-methyl-6-(trifluoromethyl)pyridine; 4-Methyl-2-chloro-6-(trifluoromethyl)pyridine; 2-Chloro-4-methyl-6-(trifluoromethyl)azine; 2-Chloro-4-methyl-6-trifluoromethylazine
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-4-Methyl-6-(Trifluoromethyl)pyridine is produced and analyzed under strict quality management protocols to ensure consistency and purity for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality systems are designed to support cGMP and ISO standards for traceability and reliability, making this material suitable for regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and oxidizing agents. Due to its organic solvent nature and light-sensitive properties, containers should be kept sealed when not in use to maintain purity and prevent contamination.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (GC)	≥ 96.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.