Description

1-(4-Fluoro-Phenyl)-1-Pyridin-2-Yl-2-[1,2,4]Triazol-1-Yl-Ethanol is a high-purity, non-racemic chiral alcohol derivative featuring a unique molecular scaffold combining fluorophenyl, pyridyl, and triazole functionalities. This compound serves as a critical advanced pharmaceutical intermediate (API) for the research and synthesis of novel active ingredients. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing next-generation therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of potential antifungal, antiviral, and CNS-active drug candidates.
• Agrochemical Research: Used in developing novel pesticides and fungicides, leveraging the biological activity of the triazole and fluorophenyl groups.
• Chemical Biology Probe: Serves as a precursor for creating molecular probes to study enzyme inhibition and receptor-ligand interactions.
• Asymmetric Synthesis: Employed as a chiral auxiliary or starting material in stereoselective synthesis due to its defined stereocenter.
• Material Science Research: Investigated as a monomer or functional component for specialty polymers and advanced organic materials.

Basic Information

Product Name	1-(4-Fluoro-Phenyl)-1-Pyridin-2-Yl-2-[1,2,4]Triazol-1-Yl-Ethanol
CAS No.	749255-14-9
Molecular Formula	C15H13FN4O
Molecular Weight	284.29 g/mol
Synonyms	1-(4-Fluorophenyl)-1-(pyridin-2-yl)-2-(1H-1,2,4-triazol-1-yl)ethanol; 1-(4-Fluorophenyl)-1-(2-pyridyl)-2-(1,2,4-triazol-1-yl)ethanol; (RS)-1-(4-Fluorophenyl)-1-(pyridin-2-yl)-2-(1H-1,2,4-triazol-1-yl)ethan-1-ol; 749255-14-9; α-(1H-1,2,4-Triazol-1-yl)-4-fluoro-α-(2-pyridinyl)benzenemethanol
EINECS	Contact for details

Quality Control

Our production of 1-(4-Fluoro-Phenyl)-1-Pyridin-2-Yl-2-[1,2,4]Triazol-1-Yl-Ethanol adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including chiral purity analysis, to ensure it meets the exacting standards required for pharmaceutical development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (or as required)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.