Description

1H-Pyrrolo[2,3-B]Pyridine-5-Methanamine,3-Fluoro-(9Ci) is a high-purity fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a critical intermediate in the development of novel pharmaceutical agents, particularly in kinase inhibitor research and other targeted therapeutic areas. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate its unique pyrrolopyridine scaffold into new molecular entities.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), especially in kinase inhibitor programs for oncology and inflammatory diseases.
• Agrochemical Research: Used in the discovery and development of new crop protection agents and herbicides, leveraging its heterocyclic structure.
• Chemical Biology & Proteomics: Serves as a versatile scaffold for designing molecular probes and tool compounds to study biological pathways.
• Material Science Precursor: Potential use in the synthesis of advanced organic materials, such as ligands for catalysts or components in organic electronics.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research organizations for bespoke synthesis projects requiring fluorinated nitrogen heterocycles.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine-5-Methanamine,3-Fluoro-(9Ci)
CAS No.	749196-06-3
Molecular Formula	C9H8FN3
Molecular Weight	177.18 g/mol
Synonyms	3-Fluoro-1H-pyrrolo[2,3-b]pyridine-5-methanamine; 3-Fluoro-5-(aminomethyl)-1H-pyrrolo[2,3-b]pyridine; 5-(Aminomethyl)-3-fluoro-1H-pyrrolo[2,3-b]pyridine; 3-Fluoro-1H-pyrrolo[2,3-b]pyridin-5-ylmethanamine; 749196-06-3; 3-Fluoro-5-aminomethyl-1H-pyrrolo[2,3-b]pyridine; 3-Fluoro-1H-pyrrolo[2,3-b]pyridine-5-methylamine
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-B]Pyridine-5-Methanamine,3-Fluoro-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support development and commercial projects with quality documentation suitable for regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.