Description

2H-Pyran-2-Carboxylicacid,5-Aminotetrahydro-,cis-(9Ci) is a specialized heterocyclic building block featuring a fused pyran-carboxylic acid structure with an amino substituent. This compound matters as a key chiral intermediate for the synthesis of complex pharmaceuticals and bioactive molecules, enabling the construction of novel chemical entities. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for drug discovery and advanced material synthesis.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and metabolic disorder therapeutics.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and plant growth regulators that require specific stereochemistry for efficacy.
• Ligand and Catalyst Development: Serves as a precursor for designing novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Peptidomimetics and Bioisosteres: The structural motif is valuable for designing peptide mimics and bioisosteric replacements in medicinal chemistry programs.
• Academic and Contract Research: Employed in university and CRO (Contract Research Organization) settings for methodological studies and exploring new chemical space.
• Fine Chemical Production: Used in the custom synthesis of high-value, low-volume specialty chemicals for various industrial applications.

Basic Information

Product Name	2H-Pyran-2-Carboxylicacid,5-Aminotetrahydro-,cis-(9Ci)
CAS No.	749175-42-6
Molecular Formula	C7H11NO3
Molecular Weight	157.17 g/mol
Synonyms	cis-5-Aminotetrahydro-2H-pyran-2-carboxylic acid; (2R,5S)-5-Aminotetrahydro-2H-pyran-2-carboxylic acid; 5-Amino-tetrahydro-pyran-2-carboxylic acid; 2H-Pyran-2-carboxylic acid, 5-aminohexahydro-, cis-; 749175-42-6; cis-5-ATHPCA; (cis)-5-Aminotetrahydropyran-2-carboxylic Acid
EINECS	Contact for details

Quality Control

Our 2H-Pyran-2-Carboxylicacid,5-Aminotetrahydro-,cis-(9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.