Description

tert-Butyl 5-Formyl-3-Methylpyridin-2-Ylcarbamate is a high-purity, advanced pharmaceutical intermediate characterized by its pyridine core with formyl and carbamate protecting groups. This compound is a critical building block in modern organic synthesis, enabling the efficient construction of complex molecules for therapeutic applications. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs), particularly in areas requiring sophisticated heterocyclic chemistry.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those targeting neurological and oncological pathways.
• Organic Synthesis Building Block: Used for introducing protected amine and aldehyde functionalities in multi-step synthetic routes for fine chemicals.
• Agrochemical Research: Serves as a starting material for developing new active ingredients in crop protection products.
• Academic & R&D Laboratories: Employed in methodological research and the discovery of new chemical entities (NCEs).
• Peptide Mimetic Development: Useful in creating peptidomimetics where the pyridine ring acts as a bioisostere.

Basic Information

Product Name	tert-Butyl 5-Formyl-3-Methylpyridin-2-Ylcarbamate
CAS No.	748812-79-5
Molecular Formula	C12H16N2O3
Molecular Weight	236.27 g/mol
Synonyms	2-[[(1,1-Dimethylethoxy)carbonyl]amino]-5-formyl-3-methylpyridine; 2-((tert-Butoxycarbonyl)amino)-5-formyl-3-methylpyridine; tert-Butyl (5-formyl-3-methylpyridin-2-yl)carbamate; 5-Formyl-3-methylpyridin-2-yl-carbamic acid tert-butyl ester; Boc-2-amino-5-formyl-3-methylpyridine; 748812-79-5; 2-Pyridinecarboxamide, N-(1,1-dimethylethyl)-5-formyl-3-methyl-
EINECS	Contact for details

Quality Control

Our tert-Butyl 5-Formyl-3-Methylpyridin-2-Ylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized and should be stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.