Description

Cyclopentanecarboxylic Acid, 2-Amino-5-Methyl-, Methyl Ester, (1Alpha,2Alpha,5Alpha)- CAS NO 748743-26-2 is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. This compound matters because its unique bicyclic structure, featuring multiple chiral centers and functional groups, makes it a critical intermediate for constructing complex molecular architectures. Pharmaceutical and agrochemical research organizations need it for the development of novel active ingredients, particularly in the synthesis of stereospecific drug candidates and high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and antiviral therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced, stereoselective pesticides and herbicides where specific spatial orientation is crucial for biological activity.
• Asymmetric Catalysis: Serves as a precursor or ligand in the development of chiral catalysts for enantioselective synthesis.
• Fine Chemical Production: Employed in the manufacture of complex fragrance molecules, flavors, and other high-value specialty chemicals requiring precise stereochemistry.
• Academic & Industrial Research: A valuable tool for methodological development in organic chemistry, particularly in studies involving cyclopentane ring systems and stereocontrol.
• Peptidomimetics & Proline Analogs: Its structure makes it suitable for creating constrained peptide analogs and non-natural amino acid derivatives for drug discovery.

Basic Information

Product Name	Cyclopentanecarboxylic Acid, 2-Amino-5-Methyl-, Methyl Ester, (1Alpha,2Alpha,5Alpha)-
CAS No.	748743-26-2
Molecular Formula	C9H17NO2
Molecular Weight	171.24 g/mol
Synonyms	(1R,2R,5R)-2-Amino-5-methylcyclopentanecarboxylic acid methyl ester; Methyl (1R,2R,5R)-2-amino-5-methylcyclopentanecarboxylate; (1α,2α,5α)-2-Amino-5-methylcyclopentanecarboxylic acid methyl ester; (1R,2R,5R)-2-Amino-5-methyl-1-cyclopentanecarboxylic acid methyl ester; Methyl (1R,2R,5R)-2-amino-5-methyl-1-cyclopentanecarboxylate; (1R,2R,5R)-2-Amino-5-methylcyclopentane-1-carboxylic acid methyl ester; CAS 748743-26-2
EINECS	Contact for details

Quality Control

Our Cyclopentanecarboxylic Acid, 2-Amino-5-Methyl-, Methyl Ester, (1Alpha,2Alpha,5Alpha)- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure compliance with exacting research and pharmaceutical-grade standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided to guarantee traceability and batch-to-batch consistency for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.