Description

1-Oxaspiro[4.5]Decane-2,6-Diol, 4,4,8-Trimethyl-, (5R,6S,8R)- (9Ci) is a high-purity, stereochemically defined spirocyclic diol building block. This compound matters as a sophisticated chiral intermediate, offering precise three-dimensional structure for advanced synthetic chemistry. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex natural product analogs.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting complex molecular architectures.
• Agrochemical Synthesis: Used in the creation of advanced, stereospecific pesticides and herbicides where the specific spatial orientation of the molecule is critical for biological activity.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for the synthesis of novel chiral ligands and organocatalysts used in enantioselective transformations.
• Fine Chemical and Specialty Chemical Production: Employed in the multistep synthesis of high-value, complex fine chemicals and flavors & fragrances.
• Academic and Industrial R&D: A valuable tool for methodological development in organic synthesis and for exploring new chemical space in material science.

Basic Information

Product Name	1-Oxaspiro[4.5]Decane-2,6-Diol, 4,4,8-Trimethyl-, (5R,6S,8R)- (9Ci)
CAS No.	748142-72-5
Molecular Formula	C12H22O3
Molecular Weight	214.30 g/mol
Synonyms	(5R,6S,8R)-4,4,8-Trimethyl-1-oxaspiro[4.5]decane-2,6-diol; 4,4,8-Trimethyl-1-oxaspiro[4.5]decane-2,6-diol (5R,6S,8R)-; Trimethyloxaspirodecandiol; Spirocyclic diol intermediate; (5R,6S,8R)-isomer of 1-Oxaspiro[4.5]decane-2,6-diol, 4,4,8-Trimethyl-
EINECS	Contact for details

Quality Control

Every batch of our 1-Oxaspiro[4.5]Decane-2,6-Diol, 4,4,8-Trimethyl-, (5R,6S,8R)- (9Ci) is produced under strict quality management protocols. We employ advanced analytical techniques including HPLC, GC, and chiral analysis to ensure high chemical and enantiomeric purity, meeting the stringent requirements of research and cGMP-grade manufacturing. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.