Description

6-Bromo-5-Methyl[1,2,4]Triazolo[1,5-A]Pyridine is a high-purity, heterocyclic organic building block of significant interest in advanced chemical synthesis. This compound serves as a critical intermediate for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, enabling the construction of complex molecular architectures. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to introduce specific bromo-substituted triazolopyridine motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in kinase inhibitor and antiviral therapeutic areas.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science Research: Serves as a precursor for organic electronic materials, such as ligands for OLEDs or molecular sensors.
• Chemical Biology Probes: Employed in the synthesis of tagged molecules for studying biological pathways and protein interactions.
• Cross-Coupling Reactions: The bromo substituent makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Library Synthesis for HTS: A valuable building block for generating diverse compound libraries used in high-throughput screening (HTS) campaigns.

Basic Information

Product Name	6-Bromo-5-Methyl[1,2,4]Triazolo[1,5-A]Pyridine
CAS No.	746668-59-7
Molecular Formula	C7H5BrN4
Molecular Weight	225.05 g/mol
Synonyms	6-Bromo-5-methyl-[1,2,4]triazolo[1,5-a]pyridine; 5-Methyl-6-bromo[1,2,4]triazolo[1,5-a]pyridine; [1,2,4]Triazolo[1,5-a]pyridine, 6-bromo-5-methyl-; 6-Bromo-5-methyl-1,2,4-triazolo[1,5-a]pyridine; 746668-59-7; 6-Bromo-5-methyltriazolopyridine
EINECS	Contact for details

Quality Control

Our 6-Bromo-5-Methyl[1,2,4]Triazolo[1,5-A]Pyridine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and scale-up. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality systems are designed to meet the rigorous standards required for pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Single Impurity (HPLC)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.