Description

6-Iodo-2-Methyl-[1,2,4]Triazolo[1,5-A]Pyridine is a high-value heterocyclic building block and advanced pharmaceutical intermediate. This compound is critical for medicinal chemistry research and the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of targeted therapies. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific halogenated triazolopyridine motifs into their molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, especially for kinase inhibitors and other small-molecule therapeutics.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization due to its reactive iodine handle for cross-coupling reactions (e.g., Suzuki, Sonogashira).
• Agrochemical Research: Employed in the synthesis of novel herbicides, fungicides, and insecticides that incorporate the triazolopyridine scaffold.
• Material Science: Potential building block for creating organic electronic materials, ligands for catalysis, or functional dyes.
• Chemical Biology: Can be used as a probe or tag in bioconjugation and labeling applications.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for client projects.

Basic Information

Product Name	6-Iodo-2-Methyl-[1,2,4]Triazolo[1,5-A]Pyridine
CAS No.	746668-57-5
Molecular Formula	C7H6IN3
Molecular Weight	259.05 g/mol
Synonyms	2-Methyl-6-iodo-[1,2,4]triazolo[1,5-a]pyridine; 6-Iodo-2-methyl-[1,2,4]triazolo[1,5-a]pyridine; 2-Methyl-6-iodo-1,2,4-triazolo[1,5-a]pyridine; 6-Iodo-2-methyl-1,2,4-triazolo[1,5-a]pyridine; IMTAP; Triazolopyridine Iodide Derivative
EINECS	Contact for details

Quality Control

Our 6-Iodo-2-Methyl-[1,2,4]Triazolo[1,5-A]Pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency essential for sensitive R&D and scale-up processes. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment. For long-term storage, consider using inert gas purging.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.