Description

Ethyl 2-(6-Bromopyridin-3-Yl)-2-Oxoacetate is a high-purity brominated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure makes it a versatile intermediate for constructing complex heterocyclic compounds and active pharmaceutical ingredients (APIs). This compound is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of advanced pesticides, herbicides, and fungicides with specific biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the synthesis of organic electronic materials and functional polymers.
• Custom Synthesis and Contract Manufacturing: A vital component for custom synthesis houses producing bespoke chemicals for client R&D programs.

Basic Information

Product Name	Ethyl 2-(6-Bromopyridin-3-Yl)-2-Oxoacetate
CAS No.	745816-48-2
Molecular Formula	C9H8BrNO3
Molecular Weight	258.07 g/mol
Synonyms	Ethyl 6-bromonicotinoylformate; 2-Oxo-2-(6-bromo-3-pyridinyl)ethyl acetate; Ethyl (6-bromopyridin-3-yl)glyoxylate; 6-Bromonicotinoylformic acid ethyl ester; 745816-48-2; Ethyl α-oxo-6-bromonicotinate; Acetic acid, 2-(6-bromo-3-pyridinyl)-2-oxo-, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 2-(6-Bromopyridin-3-Yl)-2-Oxoacetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.