Description

Benzene, 1-[(1S)-1-Isocyanatoethyl]-4-Methoxy- (9Ci) is a specialized chiral isocyanate derivative, a high-value building block in advanced organic synthesis. This compound is critical for introducing a reactive isocyanate group with defined stereochemistry into target molecules, enabling the creation of novel materials with precise properties. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of chiral ureas, carbamates, and other functionalized intermediates.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring stereochemical control.
• Agrochemical Synthesis: Used in the development of novel, high-performance pesticides and herbicides where specific stereoisomers exhibit enhanced biological activity.
• Polymer & Material Science: Serves as a monomer or cross-linking agent for producing specialty polyurethanes, coatings, and adhesives with tailored performance characteristics.
• Chemical Research: An essential reagent in academic and industrial R&D for exploring new synthetic methodologies and creating libraries of chiral compounds.
• Liquid Crystal & OLED Materials: Potential precursor for synthesizing advanced functional materials used in display technologies.

Basic Information

Product Name	Benzene, 1-[(1S)-1-Isocyanatoethyl]-4-Methoxy- (9Ci)
CAS No.	745783-83-9
Molecular Formula	C10H11NO2
Molecular Weight	177.20 g/mol
Synonyms	(S)-1-(4-Methoxyphenyl)ethyl isocyanate; 1-[(1S)-1-Isocyanatoethyl]-4-methoxybenzene; p-Methoxy-α-methylbenzyl isocyanate, (S)-; (S)-α-Methyl-4-methoxybenzyl isocyanate; (S)-1-Isocyanato-1-(4-methoxyphenyl)ethane; (S)-MEBI; (S)-p-Methoxy-α-methylbenzyl isocyanate
EINECS	Contact for details

Quality Control

Our Benzene, 1-[(1S)-1-Isocyanatoethyl]-4-Methoxy- (9Ci) is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure high chemical and enantiomeric purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon). Due to its hygroscopic and moisture-sensitive nature, containers must be kept sealed and allowed to reach room temperature before opening to prevent condensation and hydrolysis. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.