Description

(S)-(+)-1-Indanyl Isocyanate is a chiral, enantiomerically pure building block of significant interest in advanced organic synthesis. Its value lies in its role as a key precursor for introducing the rigid, lipophilic indane scaffold with defined stereochemistry into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients, particularly for applications requiring specific three-dimensional interactions.

Application

• Chiral intermediate in the synthesis of pharmaceutical candidates, especially protease inhibitors and other enzyme-targeted therapies.
• Building block for advanced materials, such as chiral liquid crystals or polymers with specific optical properties.
• Key reagent in the development of agrochemicals where stereochemistry impacts biological activity and environmental profile.
• Precursor for chiral ligands and catalysts used in asymmetric synthesis.
• Research and development of novel chemical entities in medicinal chemistry and material science.

Basic Information

Product Name	(S)-(+)-1-Indanyl Isocyanate
CAS No.	745783-81-7
Molecular Formula	C10H9NO
Molecular Weight	159.19 g/mol
Synonyms	(1S)-1,2-Dihydro-1H-inden-1-yl isocyanate; (S)-1-Indanyl isocyanate; (S)-(+)-1,2-Dihydro-1H-inden-1-yl isocyanate; (+)-(S)-1-Indanyl isocyanate; (S)-Indan-1-yl isocyanate; (1S)-Indanyl isocyanate; (S)-1-Azidoindane (precursor); (S)-1-Isocyanatoindane
EINECS	Contact for details

Quality Control

Our (S)-(+)-1-Indanyl Isocyanate is produced under strict quality management protocols to ensure high enantiomeric purity and chemical consistency. Each batch is characterized using advanced analytical techniques including chiral HPLC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profile is provided with every shipment to support your R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. This product is hygroscopic (moisture-sensitive) and should be stored under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place. Recommended storage temperature is 2-8°C for long-term stability. Allow the sealed container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.