Description

(R)-(-)-1-Indanyl Isocyanate is a high-purity, chiral isocyanate building block of significant importance in asymmetric synthesis. This compound matters for its role as a key intermediate in the development of enantiomerically pure pharmaceuticals and advanced materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures with defined stereochemistry.

Application

• Pharmaceutical Intermediate: A critical chiral precursor for the synthesis of active pharmaceutical ingredients (APIs) and investigational drugs, particularly those targeting neurological and cardiovascular diseases.
• Agrochemical Synthesis: Used in the research and development of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Chiral Ligand & Catalyst Development: Serves as a building block for creating novel chiral ligands and organocatalysts used in asymmetric catalysis.
• Advanced Material Research: Employed in the synthesis of specialty polymers and liquid crystals where the indanyl moiety imparts specific rigidity and optical properties.
• Peptidomimetics & Bioactive Molecules: Utilized to introduce the indanyl group into peptide backbones and other bioactive scaffolds to modulate biological activity and metabolic stability.
• Chemical Biology Probes: Acts as a reactive handle for labeling and modifying biomolecules in proteomics and chemical biology research.

Basic Information

Product Name	(R)-(-)-1-Indanyl Isocyanate
CAS No.	745783-80-6
Molecular Formula	C10H9NO
Molecular Weight	159.19 g/mol
Synonyms	(R)-1-Indanyl isocyanate; (1R)-2,3-Dihydro-1H-inden-1-yl isocyanate; (-)-(R)-1-Indanyl isocyanate; (R)-(-)-Indan-1-yl isocyanate; (R)-1-Isocyanatoindane; (R)-Indanyl isocyanate; (1R)-Indanyl isocyanate; 1-Indanyl isocyanate, (R)-(-)-
EINECS	Contact for details

Quality Control

Our (R)-(-)-1-Indanyl Isocyanate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with exacting standards for research and development. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its moisture-sensitive (hygroscopic) nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.