Description

(R)-(-)-2-Hexyl Isocyanate is a chiral isocyanate building block of significant importance in asymmetric synthesis. Its value lies in its ability to introduce the hexyl isocyanate moiety with high stereochemical control, enabling the production of enantiomerically pure compounds. This product is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing advanced active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), including potential enzyme inhibitors and receptor modulators.
• Agrochemical Synthesis: Used in the research and development of chiral pesticides and herbicides, where specific stereochemistry can be critical for biological activity and environmental safety.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands, organocatalysts, and metal-organic frameworks (MOFs) used in asymmetric catalysis.
• Polymer Modification: Employed to introduce chiral centers into specialty polymers, polyurethanes, and resins to impart specific physical or optical properties.
• Chemical Biology Probes: Utilized in the synthesis of isocyanate-containing probes for studying enzyme mechanisms and protein labeling.
• Fine Chemical Production: A versatile intermediate for the manufacture of complex, high-value chiral compounds for various research and industrial applications.

Basic Information

Item	Details
Product Name	(R)-(-)-2-Hexyl Isocyanate
CAS No.	745783-77-1
Molecular Formula	C7H13NO
Molecular Weight	127.18 g/mol
Synonyms	(R)-2-Hexyl isocyanate; (R)-(-)-2-Hexylisocyanate; (2R)-Hexyl isocyanate; (R)-1-Isocyanatohexane; (-)-(R)-2-Hexyl Isocyanate; (R)-Hexan-2-yl isocyanate; (R)-sec-Hexyl isocyanate
EINECS	Contact for details

Quality Control

Our (R)-(-)-2-Hexyl Isocyanate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC or GC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its moisture-sensitive (hygroscopic) nature, containers should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC/GC)	≥ 98.0% ee
Water Content (Karl Fischer)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.