Description

(S)-(-)-1-(4-Chlorophenyl)Ethyl Isocyanate: Tech., 90% is a chiral isocyanate building block of significant importance in asymmetric synthesis. This compound matters as a key intermediate for introducing the (S)-1-(4-chlorophenyl)ethyl moiety into target molecules, enabling the production of enantiomerically pure pharmaceuticals and agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing chiral ureas, carbamates, and other high-value derivatives.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the production of enantiomerically pure herbicides, fungicides, and insecticides where specific stereochemistry is required for optimal activity.
• Chiral Ligand & Catalyst Preparation: Serves as a precursor for synthesizing chiral auxiliaries, ligands for asymmetric catalysis, and organocatalysts.
• Polymer Modification: Employed to introduce chiral, aromatic side-chains into specialty polymers, potentially altering their physical and optical properties.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.
• Research & Development: Essential for academic and industrial research focused on novel synthetic methodologies and the exploration of new chiral chemical space.

Basic Information

Product Name	(S)-(-)-1-(4-Chlorophenyl)Ethyl Isocyanate: Tech., 90%
CAS No.	745783-72-6
Molecular Formula	C9H8ClNO
Molecular Weight	181.62 g/mol
Synonyms	(S)-1-(4-Chlorophenyl)ethyl isocyanate; (S)-α-Methyl-4-chlorobenzyl isocyanate; (-)-1-(4-Chlorophenyl)ethyl isocyanate; (S)-(-)-1-(p-Chlorophenyl)ethyl isocyanate; (S)-1-(4-Chlorophenyl)ethan-1-yl isocyanate; (S)-CEIC; (S)-1-(4-Chlorophenyl)ethyl isocyanatobenzene
EINECS	Contact for details

Quality Control

Our technical grade (S)-(-)-1-(4-Chlorophenyl)Ethyl Isocyanate undergoes rigorous quality testing to ensure batch-to-batch consistency and reliability for synthetic applications. While this grade is optimized for cost-effective industrial use, we maintain strict in-process controls to confirm identity, purity, and the absence of critical impurities. Certificates of Analysis (COA) detailing key parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition by atmospheric moisture. Keep away from heat, sparks, open flames, and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (HPLC)	≥ 90.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.