Description

(1S,2S)-(+)-2-Benzyloxycyclopentyl Isocyanate is a chiral, enantiomerically pure isocyanate derivative featuring a benzyl-protected cyclopentanol scaffold. This compound matters as a high-value, stereochemically defined building block crucial for the synthesis of complex molecules where spatial orientation is critical for biological activity or material properties. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing novel active ingredients, chiral ligands, and advanced polymers.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the research and production of enantiomerically pure pesticides and herbicides, where specific stereochemistry can enhance efficacy and reduce environmental impact.
• Chiral Ligand & Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands and organocatalysts used in asymmetric synthesis.
• Advanced Material Research: Employed in the development of specialty polymers, polyurethanes, and coatings with tailored properties for high-performance applications.
• Peptidomimetics & Bioconjugation: Useful for introducing the isocyanate functional group into peptide backbones or for bioconjugation strategies in medicinal chemistry.
• Academic & Contract Research: A valuable reagent for methodological development in organic synthesis and for exploring new chemical spaces in academic and industrial R&D settings.

Basic Information

Product Name	(1S,2S)-(+)-2-Benzyloxycyclopentyl Isocyanate
CAS No.	745783-70-4
Molecular Formula	C13H15NO2
Molecular Weight	217.26 g/mol
Synonyms	(1S,2S)-2-(Benzyloxy)cyclopentyl isocyanate; (+)-(1S,2S)-2-Benzyloxycyclopentyl isocyanate; (1S,2S)-rel-2-(Phenylmethoxy)cyclopentyl isocyanate; 2-Benzyloxycyclopentyl isocyanate, (1S,2S)-(+)-; Cyclopentanol, 2-(phenylmethoxy)-, 1-isocyanate-, (1S,2S)-; BnO-Cyp-NCO
EINECS	Contact for details

Quality Control

Our (1S,2S)-(+)-2-Benzyloxycyclopentyl Isocyanate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure high chemical and enantiomeric purity suitable for demanding synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic and moisture-sensitive nature, it is recommended to handle and store the material under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.