Description

1H-Pyrrolo[2,3-B]Pyridine, 4-Chloro-1-(Phenylsulfonyl)- is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 744209-63-0. This compound is a critical building block in modern medicinal chemistry, valued for its role in constructing complex heterocyclic scaffolds. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and commercial production of kinase inhibitor drugs.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies for new drug candidates.
• Organic Synthesis Building Block: Employed in the construction of complex fused heterocyclic systems common in agrochemicals and materials science.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the life sciences industry.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine, 4-Chloro-1-(Phenylsulfonyl)-
CAS No.	744209-63-0
Molecular Formula	C13H9ClN2O2S
Molecular Weight	292.74 g/mol
Synonyms	4-Chloro-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine; 4-Chloro-1H-pyrrolo[2,3-b]pyridine 1-(phenylsulfonyl) derivative; 4-Chloro-1-tosyl-7-azaindole (common name); 4-Chloro-1-(benzenesulfonyl)-1H-pyrrolo[2,3-b]pyridine; 744209-63-0; 1-(Phenylsulfonyl)-4-chloro-1H-pyrrolo[2,3-b]pyridine
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-B]Pyridine, 4-Chloro-1-(Phenylsulfonyl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing specifications such as assay (HPLC), related substances, and residual solvents is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container sealed to protect this moisture-sensitive material from humidity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.