Description

Spiro[3H-Indole-3,3-Pyrrolidin]-2(1H)-One, 1-Ethyl-7-Methyl- (9Ci) is a high-value, complex spirocyclic indole derivative that serves as a critical advanced intermediate in modern synthetic chemistry. Its unique fused ring structure makes it a versatile building block for constructing novel molecular architectures with potential biological activity. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of new active ingredients and for use in method development and scale-up studies.

Application

• Pharmaceutical Intermediate: A key precursor in the research and synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, due to its privileged indole-pyrrolidine scaffold.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where its complex structure can contribute to unique modes of action.
• Chemical Biology Probe: Serves as a core structure for designing molecular probes to study enzyme function and protein-protein interactions in biological systems.
• Material Science Research: Investigated as a building block for organic electronic materials and specialty polymers, leveraging its rigid, conjugated framework.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in organic synthesis, including novel cyclization and functionalization reactions.

Basic Information

Product Name	Spiro[3H-Indole-3,3-Pyrrolidin]-2(1H)-One, 1-Ethyl-7-Methyl- (9Ci)
CAS No.	744146-12-1
Molecular Formula	C14H16N2O
Molecular Weight	228.29 g/mol
Synonyms	1-Ethyl-7-methylspiro[3H-indole-3,3'-pyrrolidin]-2(1H)-one; 1-Ethyl-7-methyl-1,2-dihydrospiro[3H-indole-3,3'-pyrrolidin]-2-one; 744146-12-1; Spiro[indole-3,3'-pyrrolidin]-2-one, 1-ethyl-7-methyl-; 1-Ethyl-7-methylspiro[indoline-3,3'-pyrrolidin]-2-one
EINECS	Contact for details

Quality Control

Our Spiro[3H-Indole-3,3-Pyrrolidin]-2(1H)-One, 1-Ethyl-7-Methyl- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization using techniques such as HPLC, NMR, and MS to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all relevant specifications are provided with every shipment. We support cGMP compliance for advanced intermediates intended for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.