Description

Cyclobutanemethanol, 3-Hydroxy-2-Methylene-, α-Acetate, (1S,3S)- (9Ci) is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. Its unique fused cyclobutane ring system with hydroxyl and acetoxy functionalities makes it a valuable precursor for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and fine chemical industries for applications in medicinal chemistry and asymmetric synthesis.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for candidates with complex cyclic structures.
• Asymmetric Synthesis: Utilized as a building block in stereoselective reactions to introduce the (1S,3S) configuration into target molecules, crucial for developing enantiomerically pure compounds.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization processes to explore new chemical space and biological activity.
• Fine Chemical Synthesis: Acts as a precursor for the synthesis of specialty chemicals, fragrances, and advanced materials requiring specific stereochemistry.
• Academic & Industrial R&D: Used in methodological development and exploratory synthesis within university laboratories and corporate R&D centers focused on organic and organometallic chemistry.

Basic Information

Product Name	Cyclobutanemethanol, 3-Hydroxy-2-Methylene-, α-Acetate, (1S,3S)- (9Ci)
CAS No.	743477-88-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	(1S,3S)-3-Hydroxy-2-methylenebutyl acetate; (1S,3S)-3-Hydroxy-2-methylenebutyl ethanoate; 3-Hydroxy-2-methylenebutyl acetate, (1S,3S)-; Cyclobutanemethanol, 3-hydroxy-2-methylene-, α-acetate, (1S,3S)-; (1S,3S)-3-Hydroxy-2-methylenebutyl Acetate; (1S,3S)-3-Hydroxy-2-methylenebutyl Acetate (9CI); 743477-88-5; (1S,3S)-3-Hydroxy-2-methylenebutyl Acetate (Cyclobutane Derivative)
EINECS	Contact for details

Quality Control

Our Cyclobutanemethanol, 3-Hydroxy-2-Methylene-, α-Acetate, (1S,3S)- (9Ci) is produced under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity suitable for research and development applications. Each lot is characterized using advanced analytical techniques, including HPLC, GC, NMR, and chiral analysis, to confirm identity, purity, and stereochemical integrity. Certificates of Analysis (COA) detailing all relevant specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee (1S,3S)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.