Description

1H-Pyrrolo[2,3-C]Pyridine-2-Carboxylic Acid, 2,3-Dihydro-1,2-Dihydroxy-, Ethyl Ester (9Ci) is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in oncology and antiviral research. It is primarily sought after by R&D laboratories, process development chemists, and manufacturers within the pharmaceutical and biotechnology sectors for its precise molecular architecture.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules targeting specific biological pathways.
• Oncology Research: Used in the development of kinase inhibitors and other targeted cancer therapies.
• Antiviral Drug Development: Serves as a core scaffold for compounds being investigated for antiviral activity.
• Chemical Biology & Proteomics: Employed as a molecular probe or tag in studying protein-ligand interactions.
• Process Chemistry & Scale-Up: Utilized in route scouting and optimization for the commercial production of APIs.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of client-specific novel chemical entities.

Basic Information

Item	Details
Product Name	1H-Pyrrolo[2,3-C]Pyridine-2-Carboxylic Acid, 2,3-Dihydro-1,2-Dihydroxy-, Ethyl Ester (9Ci)
CAS No.	743466-47-9
Molecular Formula	C10H12N2O4
Molecular Weight	224.21 g/mol
Synonyms	Ethyl 1,2-dihydroxy-2,3-dihydro-1H-pyrrolo[2,3-c]pyridine-2-carboxylate; 743466-47-9; 1H-Pyrrolo[2,3-c]pyridine-2-carboxylic acid, 2,3-dihydro-1,2-dihydroxy-, ethyl ester; Ethyl (1R,2S)-1,2-dihydroxy-2,3-dihydro-1H-pyrrolo[2,3-c]pyridine-2-carboxylate; 2,3-Dihydro-1,2-dihydroxy-1H-pyrrolo[2,3-c]pyridine-2-carboxylic acid ethyl ester; 1H-Pyrrolo[2,3-c]pyridine-2-carboxylic acid, 2,3-dihydro-1,2-dihydroxy-, ethyl ester, (1R,2S)-rel-
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-C]Pyridine-2-Carboxylic Acid, 2,3-Dihydro-1,2-Dihydroxy-, Ethyl Ester (9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with each shipment, detailing all specified parameters. We support development and commercial projects with material produced to GMP-grade standards upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.