Description

R-Allylglycine Ethyl Ester Hydrochloride is a high-purity chiral building block and synthetic intermediate of significant importance in advanced organic synthesis. Its core value proposition lies in its role as a key precursor for the preparation of unnatural amino acids and pharmacologically active compounds, enabling the development of novel molecules with specific stereochemistry. This product is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require enantiomerically pure intermediates for drug discovery, process development, and the synthesis of complex bioactive molecules.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel drug candidates, particularly in neurological and metabolic disorder research.
• Unnatural Amino Acid Synthesis: Serves as a versatile precursor for constructing side-chain modified, non-proteinogenic amino acids used in peptide mimetics and bioconjugation.
• Agrochemical Research: Used in the development of enantiomerically pure active ingredients for advanced crop protection agents.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes to study enzyme mechanisms and biological pathways.
• Asymmetric Synthesis: Acts as a starting material or intermediate in catalytic asymmetric transformations to introduce chiral centers.
• Peptidomimetic Development: Integral for creating peptide analogs with enhanced stability, bioavailability, and target specificity.

Basic Information

Product Name	R-Allylglycine Ethyl Ester Hydrochloride
CAS No.	743442-77-5
Molecular Formula	C8H15NO2·HCl
Molecular Weight	193.67 g/mol (Free base: 157.21)
Synonyms	(R)-2-Amino-4-pentenoic Acid Ethyl Ester Hydrochloride; Ethyl (2R)-2-Amino-4-pentenoate Hydrochloride; (R)-Ethyl 2-Amino-4-pentenoate Hydrochloride; D-Allylglycine Ethyl Ester HCl; (R)-Allylglycine Ethyl Ester HCl; (2R)-2-Amino-4-pentenoic Acid Ethyl Ester Hydrochloride; AGEE-HCl; UNII-9I3F8M3U4F
EINECS	Contact for details

Quality Control

Our R-Allylglycine Ethyl Ester Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to confirm identity, potency, and impurity profiles. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles for pharmaceutical-grade intermediates, ensuring compliance with the stringent requirements of our global clientele.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee (R-isomer)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.