Description

3-(Trifluoromethyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine is a high-value, fluorinated heterocyclic building block essential for modern pharmaceutical and agrochemical research. This compound matters because its unique trifluoromethylated pyrazolopyridine core offers significant potential for modulating the biological activity, metabolic stability, and lipophilicity of lead molecules. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical industry for the synthesis of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key synthon for the development of central nervous system (CNS) and oncology drug candidates.
• Agrochemical Research: Used in the synthesis of advanced herbicides and pesticides, leveraging the bioactivity-enhancing properties of the trifluoromethyl group.
• Chemical Biology Probe Development: Serves as a versatile scaffold for creating tool compounds to study enzyme function and biological pathways.
• Material Science Precursor: Potential building block for specialty polymers and advanced organic electronic materials.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up services.

Basic Information

Product Name	3-(Trifluoromethyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine
CAS No.	743419-80-9
Molecular Formula	C7H8F3N3
Molecular Weight	191.16 g/mol
Synonyms	3-(Trifluoromethyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine; 1H-Pyrazolo[4,3-c]pyridine, 4,5,6,7-tetrahydro-3-(trifluoromethyl)-; 743419-80-9; 3-Trifluoromethyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine; 4,5,6,7-Tetrahydro-3-(trifluoromethyl)-1H-pyrazolo[4,3-c]pyridine; Pyrazolopyridine trifluoromethyl derivative; TFMPP intermediate
EINECS	Contact for details

Quality Control

Our 3-(Trifluoromethyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.