Description

2-[4-(Trifluoromethyl)Phenyl]Imidazo[1,2-A]Pyridine is a high-value heterocyclic aromatic compound featuring a fused imidazopyridine core substituted with a trifluoromethylphenyl group. This structure is of significant interest in advanced organic synthesis, particularly for the development of novel pharmaceutical intermediates and functional materials. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate its unique fluorinated aromatic scaffold into new molecular entities.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially for targets in oncology, CNS disorders, and infectious diseases.
• Agrochemical Research: Used in the development of new active ingredients for crop protection, leveraging the bioactivity and metabolic stability often imparted by the trifluoromethyl group.
• Material Science Precursor: Serves as an organic precursor for the development of advanced functional materials, including organic light-emitting diodes (OLEDs) and charge-transport layers.
• Chemical Biology Probe: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and as a scaffold for designing enzyme inhibitors or receptor modulators.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specialized fluorinated heterocycles.

Basic Information

Product Name	2-[4-(Trifluoromethyl)Phenyl]Imidazo[1,2-A]Pyridine
CAS No.	743407-46-7
Molecular Formula	C14H9F3N2
Molecular Weight	262.23 g/mol
Synonyms	2-[4-(Trifluoromethyl)phenyl]imidazo[1,2-a]pyridine; 2-(4-Trifluoromethylphenyl)imidazo[1,2-a]pyridine; Imidazo[1,2-a]pyridine, 2-[4-(trifluoromethyl)phenyl]-; 743407-46-7; α-(4-Trifluoromethylphenyl)imidazo[1,2-a]pyridine
EINECS	Contact for details

Quality Control

Our production of 2-[4-(Trifluoromethyl)Phenyl]Imidazo[1,2-A]Pyridine adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.