Description

Pyridine, 3-[1-(Aminooxy)-2-Propynyl]- (9Ci) is a specialized pyridine derivative featuring a reactive aminooxy and a propynyl group, making it a valuable bifunctional building block for advanced organic synthesis. This compound is engineered to serve as a key intermediate in the development of complex molecules, particularly where orthogonal reactivity and selective conjugation are required. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and material science industries for constructing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A critical synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting enzyme inhibitors or bioconjugates.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents and herbicides, leveraging its unique reactive sites.
• Bioconjugation & Linker Chemistry: The aminooxy group enables efficient oxime ligation with aldehydes and ketones, making it valuable for antibody-drug conjugate (ADC) development and protein labeling.
• Polymer & Material Science: Serves as a functional monomer or cross-linking agent for creating specialty polymers with tailored properties, such as smart hydrogels or surface coatings.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying biological processes and target engagement.
• Academic & Industrial R&D: A versatile reagent for method development and exploring new synthetic pathways in organic chemistry laboratories.

Basic Information

Product Name	Pyridine, 3-[1-(Aminooxy)-2-Propynyl]- (9Ci)
CAS No.	742691-15-2
Molecular Formula	C8H8N2O
Molecular Weight	148.16 g/mol
Synonyms	3-(1-Aminooxy-2-propynyl)pyridine; 3-(1-Aminooxyprop-2-yn-1-yl)pyridine; 1-(Pyridin-3-yl)-2-propyn-1-one O-methyloxime; 3-(1-Aminooxy-2-propynyl)pyridine (9CI); 3-(1-Aminooxyprop-2-ynyl)pyridine; 3-(2-Propynylaminooxy)pyridine; 3-(Prop-2-yn-1-ylaminooxy)pyridine
EINECS	Contact for details

Quality Control

Every batch of Pyridine, 3-[1-(Aminooxy)-2-Propynyl]- (9Ci) is manufactured and tested under strict quality management protocols to ensure consistency and purity for research and development applications. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.