Description

2,8-Diazaspiro[4.5]Decane-2-Carboxylic Acid, 8-Acetyl-, 1,1-Dimethylethyl Ester is a high-value, advanced pharmaceutical intermediate featuring a complex spirocyclic and diaza scaffold. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for constructing novel bioactive molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries for the synthesis of potential drug candidates targeting central nervous system and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for neurological and psychiatric drug discovery.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its complex, three-dimensional diazaspiro structure.
• Chemical Biology Probes: Serves as a scaffold for developing tool compounds and probes to study biological pathways and protein-ligand interactions.
• Process Chemistry Development: Employed in route scouting and scale-up studies for the efficient production of target drug molecules.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	2,8-Diazaspiro[4.5]Decane-2-Carboxylic Acid, 8-Acetyl-, 1,1-Dimethylethyl Ester
CAS No.	742067-24-9
Molecular Formula	C15H26N2O3
Molecular Weight	282.38 g/mol
Synonyms	tert-Butyl 8-acetyl-2,8-diazaspiro[4.5]decane-2-carboxylate; 8-Acetyl-2,8-diazaspiro[4.5]decane-2-carboxylic acid tert-butyl ester; 2,8-Diazaspiro[4.5]decane-2-carboxylic acid, 8-acetyl-, 1,1-dimethylethyl ester; 2-(tert-Butoxycarbonyl)-8-acetyl-2,8-diazaspiro[4.5]decane; 8-Acetyl-2-Boc-2,8-diazaspiro[4.5]decane; Boc-8-acetyl-2,8-diazaspiro[4.5]decane
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support development projects with custom purity grades (from research to GMP-grade) to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.