Description

4-Pyridinecarboxamide,n-[4-(1-Aminoethyl)Cyclohexyl]-,trans-(+)-(9Ci) CAS NO 742043-06-7 is a high-purity, stereochemically defined organic compound featuring a pyridinecarboxamide core linked to an aminoethyl-substituted cyclohexyl group. This specific trans-(+) isomer is a valuable chiral building block and intermediate in advanced synthetic chemistry. It is primarily utilized by research institutions and pharmaceutical development companies engaged in the creation of novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new therapeutic agents, particularly for central nervous system (CNS) or metabolic disorder targets.
• Organic Synthesis Building Block: Used in complex multi-step syntheses to construct molecules with specific three-dimensional architectures due to its defined trans configuration and chiral centers.
• Ligand and Catalyst Precursor: The pyridine and amine functionalities make it a candidate for developing novel ligands in asymmetric catalysis or metal-organic frameworks (MOFs).
• Agrochemical Research: Employed in the discovery and synthesis of new crop protection agents and pesticides requiring specific stereochemistry for bioactivity.
• Academic and R&D Laboratories: Used in fundamental chemical research exploring new reaction methodologies, structure-activity relationships (SAR), and material science.

Basic Information

Product Name	4-Pyridinecarboxamide,n-[4-(1-Aminoethyl)Cyclohexyl]-,trans-(+)-(9Ci)
CAS No.	742043-06-7
Molecular Formula	C14H21N3O
Molecular Weight	247.34 g/mol
Synonyms	trans-(+)-N-[4-(1-Aminoethyl)cyclohexyl]isonicotinamide; (1R,4R)-N-[4-(1-Aminoethyl)cyclohexyl]pyridine-4-carboxamide; 4-Pyridinecarboxamide, N-[4-(1-aminoethyl)cyclohexyl]-, trans-(+)-; trans-(+)-N-[4-(1-Aminoethyl)cyclohexyl]-4-pyridinecarboxamide; Isonicotinamide, N-[trans-4-(1-aminoethyl)cyclohexyl]-; (+)-trans-N-[4-(1-Aminoethyl)cyclohexyl]isonicotinamide; 742043-06-7; UNII-Contact for details
EINECS	Contact for details

Quality Control

Our 4-Pyridinecarboxamide,n-[4-(1-Aminoethyl)Cyclohexyl]-,trans-(+)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC to confirm stereochemical purity and identity verification, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, chiral excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (trans-(+) isomer)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.