Description

Glycine, n-Cyclobutyl-, Ethyl Ester (9Ci) is a specialized amino acid derivative featuring a cyclobutyl substituent on the nitrogen atom and an ethyl ester protecting group. This unique structure makes it a valuable non-proteinogenic building block for advanced organic synthesis and pharmaceutical research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel peptide mimetics and bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for peptide-based therapeutics.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and plant growth regulators that incorporate modified amino acid backbones.
• Peptidomimetic Design: Acts as a constrained scaffold for creating peptide analogs with enhanced metabolic stability and bioavailability in drug discovery programs.
• Chemical Biology Probes: Employed in the synthesis of labeled compounds or molecular probes for studying biological pathways and enzyme mechanisms.
• Fine Chemical Synthesis: Functions as a versatile building block for the preparation of complex, high-value specialty chemicals and catalysts.

Basic Information

Product Name	Glycine, n-Cyclobutyl-, Ethyl Ester (9Ci)
CAS No.	742015-31-2
Molecular Formula	C8H15NO2
Molecular Weight	157.21 g/mol
Synonyms	N-Cyclobutylglycine ethyl ester; Ethyl N-cyclobutylglycinate; Glycine, N-cyclobutyl-, ethyl ester; 2-[(Cyclobutylamino)acetate] ethyl ester; Ethyl 2-(cyclobutylamino)acetate; Aminoacetic acid, N-cyclobutyl-, ethyl ester; Cyclobutylamino-acetic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Glycine, n-Cyclobutyl-, Ethyl Ester is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure high purity and consistent performance for research and development applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.