Description

3-Cyclopropyl-5,6,7,8-Tetrahydro-Pyrido[4,3-E][1,2,4]Triazine is a high-purity, advanced pharmaceutical intermediate belonging to the fused triazine class of heterocyclic compounds. Its unique bicyclic structure with a cyclopropyl substituent makes it a critical building block for medicinal chemistry research and the synthesis of novel active pharmaceutical ingredients (APIs). This compound is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Active Pharmaceutical Ingredient (API) Development: Incorporated into the synthetic route of potential APIs, particularly in central nervous system (CNS) and oncology research areas.
• Biochemical Tool Compound: Employed in biochemical assays to study enzyme inhibition and receptor binding mechanisms.
• Fine Chemical Synthesis: Utilized for constructing complex nitrogen-containing heterocycles in advanced organic synthesis.

Basic Information

Product Name	3-Cyclopropyl-5,6,7,8-Tetrahydro-Pyrido[4,3-E][1,2,4]Triazine
CAS No.	741737-39-3
Molecular Formula	C9H12N4
Molecular Weight	176.22 g/mol
Synonyms	3-Cyclopropyl-5,6,7,8-tetrahydropyrido[4,3-e][1,2,4]triazine; Pyrido[4,3-e][1,2,4]triazine, 3-cyclopropyl-5,6,7,8-tetrahydro-; 741737-39-3; 3-Cyclopropyl-5,6,7,8-tetrahydro-pyrido[4,3-e][1,2,4]triazine; 3-Cyclopropyl-5,6,7,8-tetrahydro-1,2,4-triazino[5,6-c]pyridine
EINECS	Contact for details

Quality Control

Our production of 3-Cyclopropyl-5,6,7,8-Tetrahydro-Pyrido[4,3-E][1,2,4]Triazine adheres to stringent quality management protocols. Every batch is subjected to comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the exacting standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.