Description

3-Trifluoromethyl-5,6,7,8-Tetrahydro-Pyrido[4,3-E][1,2,4]Triazine is a high-purity, advanced pharmaceutical intermediate with a unique fused heterocyclic structure. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel drug candidates targeting central nervous system and metabolic disorders. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology firms, and fine chemical manufacturers engaged in the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) for preclinical and clinical development.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new drug discovery programs.
• Biochemical Tool Compound: Serves as a research chemical for probing biological pathways and enzyme interactions in academic and industrial settings.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex, fluorinated heterocyclic molecules for specialized applications.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.

Basic Information

Product Name	3-Trifluoromethyl-5,6,7,8-Tetrahydro-Pyrido[4,3-E][1,2,4]Triazine
CAS No.	741737-36-0
Molecular Formula	C8H8F3N4
Molecular Weight	217.17 g/mol
Synonyms	3-(Trifluoromethyl)-5,6,7,8-tetrahydropyrido[4,3-e][1,2,4]triazine; 5,6,7,8-Tetrahydro-3-(trifluoromethyl)pyrido[4,3-e][1,2,4]triazine; 741737-36-0; Pyrido[4,3-e][1,2,4]triazine, 5,6,7,8-tetrahydro-3-(trifluoromethyl)-; 3-Trifluoromethyl-5,6,7,8-tetrahydro-pyrido[4,3-e][1,2,4]triazine
EINECS	Contact for details

Quality Control

Our 3-Trifluoromethyl-5,6,7,8-Tetrahydro-Pyrido[4,3-E][1,2,4]Triazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with every shipment, detailing all relevant specifications. We support development projects with custom purity grades and analytical method development upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.