Description

3,5-Dibromo-2-Methoxy-6-Trifluoromethyl-Pyridine-4-Carbaldehyde is a high-value, multi-functional pyridine derivative used as a key synthetic intermediate. This compound is particularly significant for its trifluoromethyl and bromo substituents, which are crucial for modulating the physicochemical and biological properties of target molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors, antiviral agents, and CNS-active compounds.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the trifluoromethyl group enhances lipophilicity and metabolic stability.
• Material Science Precursor: Serves as a starting material for creating functionalized ligands, organic semiconductors, and specialty polymers with tailored electronic properties.
• Cross-Coupling Reactions: The bromine atoms make it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) to construct complex heterocyclic systems.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological processes and target engagement.
• Custom Synthesis & Contract Manufacturing: A key material for fine chemical suppliers and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	3,5-Dibromo-2-Methoxy-6-Trifluoromethyl-Pyridine-4-Carbaldehyde
CAS No.	741737-02-0
Molecular Formula	C8H4Br2F3NO2
Molecular Weight	378.93 g/mol
Synonyms	4-Formyl-3,5-dibromo-2-methoxy-6-(trifluoromethyl)pyridine; 2-Methoxy-3,5-dibromo-6-(trifluoromethyl)isonicotinaldehyde; 3,5-Dibromo-2-methoxy-6-(trifluoromethyl)pyridine-4-carboxaldehyde; 6-Trifluoromethyl-3,5-dibromo-2-methoxypyridine-4-carbaldehyde; 741737-02-0; Aldehyde, 3,5-dibromo-2-methoxy-6-(trifluoromethyl)-4-pyridinecarboxaldehyde
EINECS	Contact for details

Quality Control

Our 3,5-Dibromo-2-Methoxy-6-Trifluoromethyl-Pyridine-4-Carbaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer requirements for research or cGMP applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation and to minimize degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.