Description

Ethyl 5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Picolinate is a high-purity boronic ester derivative, a crucial building block in modern synthetic chemistry. This compound matters because it serves as a versatile intermediate for constructing complex molecules via cross-coupling reactions, enabling the development of advanced materials and pharmaceuticals. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially in creating biaryl and heterobiaryl scaffolds common in active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides that require specific boronic ester functionalities for structure-activity optimization.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as polymers and small molecules for OLEDs (Organic Light-Emitting Diodes) and OFETs (Organic Field-Effect Transistors).
• Ligand and Catalyst Development: Serves as a starting material for creating novel bidentate ligands and organometallic catalysts used in asymmetric synthesis and other catalytic processes.
• Chemical Biology Probes: Utilized in the construction of molecular probes and tags for studying biological processes and protein interactions.
• Academic & Industrial R&D: A fundamental reagent in organic synthesis laboratories for methodological development and exploring new chemical spaces.

Basic Information

Product Name	Ethyl 5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Picolinate
CAS No.	741709-57-9
Molecular Formula	C16H24BNO4
Molecular Weight	305.18 g/mol
Synonyms	Ethyl 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)picolinate; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)picolinic Acid Ethyl Ester; 2-Pyridinecarboxylic acid, 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, ethyl ester; Ethyl 5-(Pinacolatoboryl)picolinate; 5-(Pinacolatoboryl)picolinic Acid Ethyl Ester; Ethyl 5-Boronopicolinate Pinacol Ester
EINECS	Contact for details

Quality Control

Our Ethyl 5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Picolinate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing identity, purity, and impurity profiles. Our quality commitment ensures the material meets the stringent requirements for research and process development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.