Description

L-Alanine, 3-Chloro-2-Methyl-, Methyl Ester (9Ci) is a specialized, non-natural amino acid derivative characterized by its chiral center and functionalized side chain. This compound serves as a versatile and high-value building block in advanced organic synthesis, enabling the introduction of a sterically hindered, halogenated alanine moiety. It is primarily utilized by research institutions and industrial R&D departments focused on pharmaceutical development, agrochemical discovery, and the synthesis of complex peptides or chiral ligands.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in protease inhibitor and peptidomimetic drug candidates.
• Agrochemical Synthesis: Used in the design and synthesis of advanced herbicides, fungicides, and plant growth regulators that require specific stereochemistry.
• Peptide Chemistry: Incorporation into custom peptide sequences to study structure-activity relationships (SAR) or to create peptides with modified backbone properties.
• Chiral Ligand & Catalyst Development: Serves as a precursor for synthesizing novel chiral auxiliaries, ligands for asymmetric catalysis, and organocatalysts.
• Chemical Biology Research: A tool compound for probing enzyme mechanisms or as a non-canonical amino acid analog in biochemical studies.
• Material Science: Potential monomer for the synthesis of specialized polymers with unique functional properties.

Basic Information

Product Name	L-Alanine, 3-Chloro-2-Methyl-, Methyl Ester (9Ci)
CAS No.	740771-74-8
Molecular Formula	C6H10ClNO2
Molecular Weight	163.60 g/mol
Synonyms	Methyl (2S)-3-chloro-2-methylalaninate; (2S)-3-Chloro-2-methylalanine methyl ester; L-3-Chloro-2-methylalanine methyl ester; Methyl L-3-chloro-2-methylalaninate; Alanine, 3-chloro-2-methyl-, methyl ester, L- (9CI); (S)-Methyl 3-chloro-2-methylalaninate
EINECS	Contact for details

Quality Control

Our production of L-Alanine, 3-Chloro-2-Methyl-, Methyl Ester (9Ci) adheres to stringent internal quality standards to ensure batch-to-batch consistency and high chemical purity. Each lot is characterized by advanced analytical techniques including HPLC, GC, chiral analysis, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation of quality.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.