Description

5-(Piperazin-1-Yl)Imidazo[1,2-A]Pyridine is a high-value pharmaceutical intermediate and heterocyclic building block, essential for modern drug discovery and development. This compound is particularly significant for its role in synthesizing bioactive molecules targeting central nervous system (CNS) disorders and other therapeutic areas. It is a critical raw material for research institutions, contract research organizations (CROs), and pharmaceutical companies engaged in the development of novel small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) for neurological and psychiatric therapeutics.
• Drug Discovery Scaffold: Serves as a privileged heterocyclic core for medicinal chemistry, enabling the creation of compound libraries for high-throughput screening.
• Kinase Inhibitor Development: Used in research programs focused on designing and optimizing kinase inhibitors for oncology and inflammatory diseases.
• Chemical Biology Probes: Employed in the development of molecular probes to study biological pathways and protein functions.
• Agrochemical Research: Potential application as a building block for novel crop protection agents and pesticides.
• Academic & Industrial R&D: Fundamental research reagent in universities and industrial labs for exploring new chemical entities and reaction methodologies.

Basic Information

Product Name	5-(Piperazin-1-Yl)Imidazo[1,2-A]Pyridine
CAS No.	739364-02-4
Molecular Formula	C11H15N5
Molecular Weight	217.27 g/mol
Synonyms	5-(Piperazin-1-yl)imidazo[1,2-a]pyridine; Imidazo[1,2-a]pyridine, 5-(1-piperazinyl)-; 5-(1-Piperazinyl)imidazo[1,2-a]pyridine; 739364-02-4; 5-Piperazin-1-yl-imidazo[1,2-a]pyridine; 5-(Piperazin-1-yl)-imidazo[1,2-a]pyridine; 5-(Piperazin-1-yl)imidazo[1,2-a]pyridine hydrochloride (salt forms may exist); 5-(1-Piperazinyl)imidazo[1,2-a]pyridine hydrochloride
EINECS	Contact for details

Quality Control

Our 5-(Piperazin-1-Yl)Imidazo[1,2-A]Pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and identity. We provide detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and supporting regulatory filings for pre-clinical and clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and purity. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.