Description

Cyclopropanecarboxylic Acid, 1-Amino-2-Methyl-, Methyl Ester, (1R-Trans)- (9Ci) is a high-purity, stereochemically defined chiral intermediate of significant importance in advanced organic synthesis. Its core value lies in its rigid cyclopropane ring and functionalized ester group, which are critical for constructing complex molecular architectures with precise spatial orientation. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of potential drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, where the cyclopropane moiety can enhance biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the manufacture of complex, high-value specialty chemicals for electronics and material science applications.
• Academic and R&D: A valuable reagent for methodological studies in organic chemistry, particularly in ring-opening and functionalization reactions.

Basic Information

Item	Detail
Product Name	Cyclopropanecarboxylic Acid, 1-Amino-2-Methyl-, Methyl Ester, (1R-Trans)- (9Ci)
CAS No.	738554-17-1
Molecular Formula	C7H13NO2
Molecular Weight	143.18 g/mol
Synonyms	(1R,2S)-1-Amino-2-methylcyclopropanecarboxylic acid methyl ester; Methyl (1R,2S)-1-amino-2-methylcyclopropanecarboxylate; (1R-trans)-1-Amino-2-methylcyclopropanecarboxylic Acid Methyl Ester; trans-1-Amino-2-methylcyclopropanecarboxylic acid methyl ester; (1R,2S)-1-Amino-2-methylcyclopropanecarboxylate; Methyl 1-amino-2-methylcyclopropanecarboxylate (trans-); Cyclopropanecarboxylic acid, 1-amino-2-methyl-, methyl ester, (1R,2S)-
EINECS	Contact for details

Quality Control

Our Cyclopropanecarboxylic Acid, 1-Amino-2-Methyl-, Methyl Ester, (1R-Trans)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure high chemical and enantiomeric purity suitable for sensitive synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.