Description

D-Serine, o-Amino-2-Methyl-, Methyl Ester (9Ci) is a specialized, non-proteinogenic amino acid derivative with a defined chiral center and ester functionalization. This high-purity chiral building block is critical for the synthesis of complex bioactive molecules, offering precise control over stereochemistry and molecular architecture. It is primarily utilized by research institutions and pharmaceutical companies engaged in advanced medicinal chemistry, peptide synthesis, and the development of novel therapeutic agents and biochemical probes.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for neurological and metabolic targets.
• Peptide Chemistry: Used in solid-phase and solution-phase peptide synthesis to introduce modified serine residues, altering peptide stability, bioavailability, or activity.
• Biochemical Research: Acts as a precursor or standard in metabolic pathway studies, enzyme substrate investigations, and receptor-ligand interaction research.
• Agrochemical Synthesis: Employed in the design and synthesis of novel, chiral herbicides or plant growth regulators with enhanced specificity.
• Material Science: Potential monomer or building block for creating specialized polymers and biomaterials with tailored properties.

Basic Information

Product Name	D-Serine, o-Amino-2-Methyl-, Methyl Ester (9Ci)
CAS No.	738548-05-5
Molecular Formula	C5H11NO3
Molecular Weight	133.15 g/mol
Synonyms	Methyl (2R)-2-amino-3-hydroxy-2-methylpropanoate; D-2-Amino-2-methyl-3-hydroxypropionic acid methyl ester; Methyl D-2-amino-2-methyl-3-hydroxypropionate; (R)-Methyl 2-amino-2-methyl-3-hydroxypropanoate; D-α-Methylserine methyl ester; o-Amino-2-methyl-D-serine methyl ester; 738548-05-5; Methyl (R)-2-amino-2-methyl-3-hydroxypropionate
EINECS	Contact for details

Quality Control

Our D-Serine, o-Amino-2-Methyl-, Methyl Ester (9Ci) is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and synthesis. A detailed Certificate of Analysis (COA) documenting identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.