Description

2-Cyclopropene-1-Carboxylicacid,1-Amino-2-Phenyl-,Methylester,(R)-(9Ci) is a chiral, non-proteinogenic amino acid derivative featuring a highly strained cyclopropene ring system. This compound is a valuable synthetic building block, prized for its unique three-dimensional structure and stereochemical integrity, which are critical for modulating biological activity and material properties. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new drug candidates, particularly for creating molecules with constrained geometries.
• Agrochemical Synthesis: Used in the design and synthesis of novel herbicides, fungicides, and insecticides where the cyclopropene moiety can impart specific biological activity.
• Chemical Biology & Proteomics: Acts as a specialized amino acid analog for studying enzyme mechanisms, protein structure, and for the development of activity-based probes.
• Material Science Research: Employed in the synthesis of novel polymers and functional materials that require rigid, stereodefined building blocks.
• Asymmetric Catalysis: Utilized as a ligand precursor or a chiral auxiliary in the development of new catalytic systems for stereoselective transformations.
• Academic & Institutional Research: A critical reagent for methodological studies in organic synthesis, focusing on cyclopropene chemistry and stereocontrol.

Basic Information

Product Name	2-Cyclopropene-1-Carboxylicacid,1-Amino-2-Phenyl-,Methylester,(R)-(9Ci)
CAS No.	737722-72-4
Molecular Formula	C11H11NO2
Molecular Weight	189.21 g/mol
Synonyms	(R)-Methyl 1-amino-2-phenylcycloprop-2-ene-1-carboxylate; Methyl (1R)-1-amino-2-phenyl-2-cyclopropene-1-carboxylate; (R)-1-Amino-2-phenylcycloprop-2-ene-1-carboxylic acid methyl ester; (R)-1-Amino-2-phenyl-2-cyclopropene-1-carboxylic acid methyl ester; (R)-APC methyl ester; 737722-72-4; (R)-Methyl APC
EINECS	Contact for details

Quality Control

Every batch of 2-Cyclopropene-1-Carboxylicacid,1-Amino-2-Phenyl-,Methylester,(R)-(9Ci) is produced and analyzed under strict quality management protocols to ensure identity, purity, and enantiomeric excess meet the high standards required for research and development. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data, including chiral purity, are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when prolonged exposure is anticipated to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.