Description

(1R,2R)-(-)-2-Benzyloxycyclopentyl Isocyanate is a chiral, enantiomerically pure isocyanate derivative, a critical building block for the synthesis of complex organic molecules. Its value lies in its high stereochemical purity, which is essential for creating compounds with specific biological activity or material properties. This product is primarily needed by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials where precise stereochemistry is paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in areas requiring stereospecificity.
• Agrochemical Research: Used in the development of enantiomerically pure pesticides and herbicides for enhanced efficacy and environmental safety.
• Ligand and Catalyst Synthesis: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Polymer Modification: Employed to introduce functional isocyanate groups into polymer chains for specialty polyurethanes and coatings with tailored properties.
• Chemical Biology Probes: Useful for labeling and modifying biomolecules to study biological pathways and interactions.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic and medicinal chemistry laboratories.

Basic Information

Product Name	(1R,2R)-(-)-2-Benzyloxycyclopentyl Isocyanate
CAS No.	737001-14-8
Molecular Formula	C13H15NO2
Molecular Weight	217.26 g/mol
Synonyms	(1R,2R)-2-(Benzyloxy)cyclopentyl isocyanate; (-)-trans-2-Benzyloxycyclopentyl isocyanate; (1R,2R)-2-Benzyloxy-1-cyclopentyl isocyanate; 2-Benzyloxycyclopentyl isocyanate, (1R,2R)-(-)-; Cyclopentyl isocyanate, 2-(benzyloxy)-, (1R,2R)-; Benzyl (1R,2R)-2-isocyanatocyclopentyl ether
EINECS	Contact for details

Quality Control

Our (1R,2R)-(-)-2-Benzyloxycyclopentyl Isocyanate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.