Description

2,6-Diamino-3-Fluoro-4-(Trifluoromethyl)Pyridine is a high-value, multi-functional pyridine derivative distinguished by its unique trifluoromethyl and fluorine substituents. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block for the synthesis of complex organic molecules. It is essential for research and production in the pharmaceutical, agrochemical, and specialty chemical industries, where its structural motifs are leveraged to modulate biological activity and physicochemical properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the fluorine and trifluoromethyl groups enhance bioavailability and environmental stability.
• Ligand and Catalyst Development: Serves as a sophisticated ligand scaffold in organometallic chemistry and catalysis for asymmetric synthesis.
• Material Science Research: Employed in the creation of specialty polymers, liquid crystals, and electronic materials due to its electron-deficient aromatic system.
• Fluorinated Compound Library: A valuable building block for medicinal chemistry and combinatorial chemistry to create libraries of fluorinated compounds for high-throughput screening.

Basic Information

Product Name	2,6-Diamino-3-Fluoro-4-(Trifluoromethyl)Pyridine
CAS No.	737000-87-2
Molecular Formula	C7H6F4N3
Molecular Weight	208.14 g/mol
Synonyms	3-Fluoro-2,6-diamino-4-(trifluoromethyl)pyridine; 4-(Trifluoromethyl)-3-fluoro-2,6-pyridinediamine; 2,6-Pyridinediamine, 3-fluoro-4-(trifluoromethyl)-; 3-Fluoro-4-trifluoromethyl-pyridine-2,6-diamine; 737000-87-2; FC-1133 (Potential research code)
EINECS	Contact for details

Quality Control

Our production of 2,6-Diamino-3-Fluoro-4-(Trifluoromethyl)Pyridine adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We support cGMP compliance for pharmaceutical applications and can tailor quality standards to meet specific customer requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.