Description

1,6-Dioxaspiro[4.5]Dec-8-En-10-Ol, (5R,10R)-Rel- (9Ci) is a high-purity, stereochemically defined spirocyclic compound serving as a sophisticated chiral building block and intermediate in advanced organic synthesis. Its unique fused ring system and defined stereochemistry make it a valuable scaffold for constructing complex molecular architectures with precise spatial orientation. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications in asymmetric synthesis and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Asymmetric Catalysis Ligand Synthesis: Used to construct complex, enantiomerically pure ligands for transition metal catalysis.
• Agrochemical Research: Serves as a building block for developing new, stereospecific pesticides and herbicides with enhanced activity.
• Fragrance & Flavor Chemistry: Potential intermediate for creating unique, complex odorants and flavor molecules with specific sensory profiles.
• Material Science: Exploration as a monomer or cross-linker for specialty polymers with tailored thermal or optical properties.
• Academic & Institutional Research: A valuable tool for methodological studies in organic synthesis and stereochemistry.

Basic Information

Item	Details
Product Name	1,6-Dioxaspiro[4.5]Dec-8-En-10-Ol, (5R,10R)-Rel- (9Ci)
CAS No.	736185-49-2
Molecular Formula	C9H12O3
Molecular Weight	168.19 g/mol
Synonyms	rel-(5R,10R)-1,6-Dioxaspiro[4.5]dec-8-en-10-ol; (5R,10R)-rel-1,6-Dioxaspiro[4.5]dec-8-en-10-ol; 1,6-Dioxaspiro[4.5]dec-8-en-10-ol, (5R,10R)-rel-; Spiro[1,3-dioxolane-2,1'-cyclohex-4'-ene]-4'-methanol, (4'R)-rel-; (rel-5R,10R)-1,6-Dioxaspiro[4.5]dec-8-en-10-ol
EINECS	Contact for details

Quality Control

Our production of 1,6-Dioxaspiro[4.5]Dec-8-En-10-Ol, (5R,10R)-Rel- (9Ci) adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high chemical purity. Quality is verified against established internal specifications using advanced analytical techniques including HPLC, GC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be sensitive to prolonged exposure to air and moisture; keep container tightly sealed under an inert atmosphere when handling.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% (for specified enantiomer)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.