Description

Imidazo[1,2-A]Pyridine-6,7,8-Triol, 5,6,7,8-Tetrahydro-5-(Hydroxymethyl)-2-Methyl-, (5R,6R,7S,8S)- (9Ci) is a high-purity, stereochemically defined advanced pharmaceutical intermediate. This compound matters for its role as a critical building block in the synthesis of complex, biologically active molecules, particularly in medicinal chemistry. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, where precise stereochemistry and high purity are non-negotiable for successful outcomes.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel drug candidates, especially in areas targeting neurological or metabolic disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its complex, polyfunctional heterocyclic structure.
• Process Chemistry Development: Serves as a starting material or intermediate in scaling up synthetic routes for active pharmaceutical ingredients (APIs).
• Academic Research: Employed in synthetic organic chemistry studies focused on methodology development for constructing complex heterocycles.
• Bioconjugation & Probe Synthesis: Potential use in creating chemical probes or tagged molecules for biochemical and diagnostic applications, leveraging its functional groups.

Basic Information

Product Name	Imidazo[1,2-A]Pyridine-6,7,8-Triol, 5,6,7,8-Tetrahydro-5-(Hydroxymethyl)-2-Methyl-, (5R,6R,7S,8S)- (9Ci)
CAS No.	736124-86-0
Molecular Formula	C9H14N2O4
Molecular Weight	214.22 g/mol
Synonyms	(5R,6R,7S,8S)-5,6,7,8-Tetrahydro-5-(hydroxymethyl)-2-methylimidazo[1,2-a]pyridine-6,7,8-triol; 5-(Hydroxymethyl)-2-methyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyridine-6,7,8-triol (stereoisomer); A stereoisomer of a tetrahydroimidazopyridine triol derivative; Advanced chiral pharmaceutical intermediate; Complex heterocyclic building block.
EINECS	Contact for details

Quality Control

Every batch of this advanced intermediate is produced and tested under a strict quality management system. We provide comprehensive Certificates of Analysis (COA) detailing purity, stereochemical integrity, and impurity profiles, typically determined by advanced analytical techniques like HPLC and NMR. Our quality commitment ensures the material meets the exacting standards required for pharmaceutical R&D and process development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere if possible and opened only in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.