Description

2-Bromo-1-(5-Bromopyridin-3-Yl)Ethanone is a high-purity brominated pyridinyl ethanone derivative, serving as a critical building block in advanced organic synthesis. This compound is valued for its reactive bromoacetyl and bromopyridinyl moieties, which enable precise functionalization and the construction of complex heterocyclic scaffolds. It is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in developing novel pesticides and herbicides by constructing pyridine-based active molecules.
• Material Science: Serves as a monomer or cross-linking agent in the development of specialty polymers and functional materials.
• Chemical Synthesis: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) for C-C and C-N bond formation.
• Ligand Synthesis: Useful for creating complex chelating ligands used in catalysis and metal-organic frameworks (MOFs).
• Academic & Contract Research: A valuable reagent for methodological studies and discovery chemistry in university and CRO laboratories.

Basic Information

Product Name	2-Bromo-1-(5-Bromopyridin-3-Yl)Ethanone
CAS No.	734504-22-4
Molecular Formula	C7H5Br2NO
Molecular Weight	278.93 g/mol
Synonyms	1-(5-Bromo-3-pyridinyl)-2-bromoethanone; 2-Bromo-1-(5-bromo-3-pyridinyl)ethan-1-one; 5-Bromo-3-(bromoacetyl)pyridine; 3-Acetyl-5-bromopyridine, 2-bromo derivative; Ethanone, 2-bromo-1-(5-bromo-3-pyridinyl)-; α-Bromo-5-bromonicotinyl ketone
EINECS	Contact for details

Quality Control

Our 2-Bromo-1-(5-Bromopyridin-3-Yl)Ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.