Description

Pyridine, 3-Fluoro-1,2-Dihydro-1-Hydroxy-4-Nitro- (9Ci) is a specialized fluorinated and nitrated pyridine derivative, a high-value building block for advanced chemical synthesis. This compound matters for its unique molecular scaffold, which combines fluorine, nitro, and hydroxyl functionalities to enable precise structural modifications in target molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Research: Used in the development of new herbicides and pesticides, where the fluorine and nitro groups contribute to biological activity and metabolic stability.
• Material Science: Acts as a monomer or functionalizing agent in the creation of specialty polymers and liquid crystals with tailored electronic or optical properties.
• Chemical Synthesis: Employed as a versatile scaffold for constructing complex heterocyclic compounds in medicinal and process chemistry.
• Academic & Institutional Research: Utilized in universities and research institutes for studying reaction mechanisms and developing new synthetic methodologies.

Basic Information

Product Name	Pyridine, 3-Fluoro-1,2-Dihydro-1-Hydroxy-4-Nitro- (9Ci)
CAS No.	733758-54-8
Molecular Formula	C5H4FN2O3
Molecular Weight	158.10 g/mol
Synonyms	3-Fluoro-1,2-dihydro-1-hydroxy-4-nitropyridine; 1-Hydroxy-3-fluoro-4-nitropyridin-1-ium; 4-Nitro-3-fluoro-1,2-dihydro-1-hydroxypyridine; 3-Fluoro-1-hydroxy-4-nitropyridin-1-ium; 1,2-Dihydro-1-hydroxy-3-fluoro-4-nitropyridine; 3-Fluoro-4-nitropyridin-1-ol; 1-Hydroxy-3-fluoro-4-nitropyridine
EINECS	Contact for details

Quality Control

Every batch of Pyridine, 3-Fluoro-1,2-Dihydro-1-Hydroxy-4-Nitro- (9Ci) is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by advanced chromatographic and spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive nature and propensity to be easily oxidized, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.