Description

tert-Butyl 2-(Trifluoromethyl)-6,7-Dihydro-3H-Imidazo[4,5-C]Pyridine-5(4H)-Carboxylate is a high-value, heterocyclic organic compound featuring a fused imidazopyridine core and a trifluoromethyl group. This advanced pharmaceutical intermediate is critical for medicinal chemistry research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers for its role in creating potential drug candidates targeting central nervous system and metabolic disorders.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, especially in medicinal chemistry programs.
• Active Pharmaceutical Ingredient (API) Development: Used in the research and process development of new APIs, particularly those with heterocyclic scaffolds.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Biochemical Tool Compound: Potential use in developing probes for studying biological targets and pathways in academic and industrial research.
• Fine Chemical Synthesis: Employed in multi-step organic syntheses to introduce complex, functionalized heterocyclic structures.

Basic Information

Product Name	tert-Butyl 2-(Trifluoromethyl)-6,7-Dihydro-3H-Imidazo[4,5-C]Pyridine-5(4H)-Carboxylate
CAS No.	733758-27-5
Molecular Formula	C13H16F3N3O2
Molecular Weight	303.28 g/mol
Synonyms	5-tert-Butoxycarbonyl-2-(trifluoromethyl)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine; tert-Butyl 2-(trifluoromethyl)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine-5-carboxylate; 2-(Trifluoromethyl)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine-5-carboxylic acid tert-butyl ester; 733758-27-5; BOC-protected 2-(trifluoromethyl)imidazopyridine; TFMI-BOC ester
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques to guarantee identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for purity, impurities, and other critical parameters are available upon request. We adhere to cGMP principles for the manufacture of pharmaceutical intermediates to support our clients' regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥97.0%
Related Substances (HPLC)	Total impurities ≤3.0%
Any single unknown impurity	≤1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.