Description

3-(Trifluoromethyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine hydrochloride is a high-purity, advanced pharmaceutical intermediate featuring a fused pyrazolopyridine core with a strategically positioned trifluoromethyl group. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel drug candidates with enhanced metabolic stability and bioavailability. It is primarily needed by R&D and production teams in the pharmaceutical and biotechnology industries for developing new therapeutic agents targeting the central nervous system, oncology, and inflammatory diseases.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel small-molecule drug candidates.
• Kinase Inhibitor Scaffold: Serves as a privileged core structure in the design and synthesis of potent kinase inhibitors for oncology applications.
• CNS Drug Development: Used in constructing molecules targeting neurological disorders due to the favorable physicochemical properties imparted by the heterocyclic system.
• Chemical Biology Probes: Employed as a building block for creating tool compounds to study biological pathways and protein function.
• Agrochemical Research: Potential application in the synthesis of new active ingredients for crop protection.
• Material Science: Exploration of its use in the development of specialty chemicals and advanced materials.

Basic Information

Product Name	3-(Trifluoromethyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine hydrochloride
CAS No.	733757-78-3
Molecular Formula	C7H9ClF3N3
Molecular Weight	239.62 g/mol
Synonyms	1H-Pyrazolo[4,3-c]pyridine, 4,5,6,7-tetrahydro-3-(trifluoromethyl)-, hydrochloride (1:1); 3-(Trifluoromethyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine HCl; 733757-78-3; 4,5,6,7-Tetrahydro-3-(trifluoromethyl)-1H-pyrazolo[4,3-c]pyridine hydrochloride; 3-Trifluoromethyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine hydrochloride
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized and controlled using advanced analytical techniques to guarantee identity, purity, and consistency. Certificates of Analysis (COA) are available upon request, detailing comprehensive specifications including assay, impurity profile, and residual solvents. We adhere to strict quality management systems suitable for cGMP and ISO environments to support our global pharmaceutical and research clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.