Description

2-Amino-3,5-difluoropyridine is a high-purity fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic placement of fluorine atoms and an amino group, which enables precise molecular modifications to enhance the properties of target compounds. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), especially in kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where fluorine incorporation improves efficacy and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and electronic materials.
• Chemical Biology Probes: Utilized to create fluorinated analogs of biological molecules for metabolic and mechanistic studies.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for bespoke chemical synthesis services targeting complex, fluorinated target molecules.

Basic Information

Product Name	2-Amino-3,5-Difluoropyridine
CAS No.	732306-31-9
Molecular Formula	C5H4F2N2
Molecular Weight	130.10 g/mol
Synonyms	3,5-Difluoropyridin-2-amine; 2-Pyridinamine, 3,5-difluoro-; 3,5-Difluoro-2-pyridinamine; 2-Amino-3,5-difluoropyridine; 3,5-Difluoro-2-aminopyridine
EINECS	Contact for details

Quality Control

Our 2-Amino-3,5-difluoropyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high standards, including cGMP manufacturing for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.